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IGF-1 regulates the growth of fibroblasts and extracellular matrix deposition in pelvic organ prolapse

This study was carried out to observe the impact of insulin-like growth factor-1 (IGF-1) on human vaginal fibroblasts (HVFs) in the context of pelvic organ prolapse (POP) and to explore its effects on mitogen-activated protein kinases (MAPK) and nuclear factor-κB (NF-κB) signaling pathways. First, i...

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Detalles Bibliográficos
Autores principales: Yin, Yitong, Han, Ying, Shi, Chang, Xia, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712242/
https://www.ncbi.nlm.nih.gov/pubmed/33336041
http://dx.doi.org/10.1515/med-2020-0216