A Recombinant Zika Virus Envelope Protein with Mutations in the Conserved Fusion Loop Leads to Reduced Antibody Cross-Reactivity upon Vaccination

Zika virus (ZIKV) is a zoonotic, human pathogenic, and mosquito-borne flavivirus. Its distribution is rapidly growing worldwide. Several attempts to develop vaccines for ZIKV are currently ongoing. Central to most vaccination approaches against flavivirus infections is the envelope (E) protein, whic...

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Detalles Bibliográficos
Autores principales: Berneck, Beatrice Sarah, Rockstroh, Alexandra, Fertey, Jasmin, Grunwald, Thomas, Ulbert, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712286/
https://www.ncbi.nlm.nih.gov/pubmed/33066262
http://dx.doi.org/10.3390/vaccines8040603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712286/
https://www.ncbi.nlm.nih.gov/pubmed/33066262
http://dx.doi.org/10.3390/vaccines8040603

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