Immune Checkpoint Blockade Enhances Immune Activity of Therapeutic Lung Cancer Vaccine

Background: Immune checkpoint blockade that downregulates T cell evasion for effective immunity has provided a renewed interest in therapeutic cancer vaccines. Methods: Utilizing murine lung cancer models, we determined: tumor burden, TIL cytolysis, immunohistochemistry, flow cytometry, RNA Sequenci...

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Detalles Bibliográficos
Autores principales: Kadam, Pournima, Singh, Ram P., Davoodi, Michael, Lee, Jay M., John, Maie St., Sharma, Sherven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712481/
https://www.ncbi.nlm.nih.gov/pubmed/33167311
http://dx.doi.org/10.3390/vaccines8040655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712481/
https://www.ncbi.nlm.nih.gov/pubmed/33167311
http://dx.doi.org/10.3390/vaccines8040655

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