Primidone blocks RIPK1-driven cell death and inflammation

The receptor-interacting serine/threonine protein kinase 1 (RIPK1) is a key mediator of regulated cell death and inflammation. Recent studies suggest that RIPK1 inhibition would fundamentally improve the therapy of RIPK1-dependent organ damage in stroke, myocardial infarction, kidney failure, and sy...

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Detalles Bibliográficos
Autores principales: Riebeling, Theresa, Jamal, Kunzah, Wilson, Rebecca, Kolbrink, Benedikt, von Samson-Himmelstjerna, Friedrich Alexander, Moerke, Caroline, Ramos Garcia, Laura, Dahlke, Eileen, Michels, Friederike, Lühder, Fred, Schunk, Domagoj, Doldi, Philipp, Tyczynski, Bartosz, Kribben, Andreas, Flüh, Charlotte, Theilig, Franziska, Kunzendorf, Ulrich, Meier, Pascal, Krautwald, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712602/
https://www.ncbi.nlm.nih.gov/pubmed/33273695
http://dx.doi.org/10.1038/s41418-020-00690-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712602/
https://www.ncbi.nlm.nih.gov/pubmed/33273695
http://dx.doi.org/10.1038/s41418-020-00690-y

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