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rAAV-Mediated Overexpression of SOX9 and TGF-β via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Scaffold-assisted gene therapy is a highly promising tool to treat articular cartilage lesions upon direct delivery of chondrogenic candidate sequences. The goal of this study was to examine the feasibility and benefits of providing highly chondroreparative agents, the cartilage-specific sex-determi...

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Detalles Bibliográficos
Autores principales: Meng, Weikun, Rey-Rico, Ana, Claudel, Mickaël, Schmitt, Gertrud, Speicher-Mentges, Susanne, Pons, Françoise, Lebeau, Luc, Venkatesan, Jagadeesh K., Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712756/
https://www.ncbi.nlm.nih.gov/pubmed/32354138
http://dx.doi.org/10.3390/nano10050855