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Structure of voltage-modulated sodium-selective NALCN-FAM155A channel complex

Resting membrane potential determines the excitability of the cell and is essential for the cellular electrical activities. The NALCN channel mediates sodium leak currents, which positively adjust resting membrane potential towards depolarization. The NALCN channel is involved in several neurologica...

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Detalles Bibliográficos
Autores principales: Kang, Yunlu, Wu, Jing-Xiang, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712781/
https://www.ncbi.nlm.nih.gov/pubmed/33273469
http://dx.doi.org/10.1038/s41467-020-20002-9