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Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila

Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, among other processes. Malignant transformations, tumor progression, the onset of some neuropathies and other disorders have been linked to misregulation of PARP-1 activity. Despite intens...

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Detalles Bibliográficos
Autores principales: Bordet, Guillaume, Lodhi, Niraj, Guo, Danping, Kossenkov, Andrew, Tulin, Alexei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712786/
https://www.ncbi.nlm.nih.gov/pubmed/33273587
http://dx.doi.org/10.1038/s41598-020-78116-5