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Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila
Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear enzyme involved in DNA repair and transcription regulation, among other processes. Malignant transformations, tumor progression, the onset of some neuropathies and other disorders have been linked to misregulation of PARP-1 activity. Despite intens...
Autores principales: | Bordet, Guillaume, Lodhi, Niraj, Guo, Danping, Kossenkov, Andrew, Tulin, Alexei V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712786/ https://www.ncbi.nlm.nih.gov/pubmed/33273587 http://dx.doi.org/10.1038/s41598-020-78116-5 |
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