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Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status

BACKGROUND: The potential benefit of risk stratification using a 4-miRNA signature in combination with MGMT promoter methylation in IDH1/2 wild-type glioblastoma patients was assessed. METHODS: Primary tumors from 102 patients with comparable treatment from the LMU Munich (n = 37), the University Ho...

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Detalles Bibliográficos
Autores principales: Unger, Kristian, Fleischmann, Daniel F, Ruf, Viktoria, Felsberg, Jörg, Piehlmaier, Daniel, Samaga, Daniel, Hess, Julia, Suresh, Marian Preetham, Mittelbronn, Michel, Lauber, Kirsten, Budach, Wilfried, Sabel, Michael, Rödel, Claus, Reifenberger, Guido, Herms, Jochen, Tonn, Jörg-Christian, Zitzelsberger, Horst, Belka, Claus, Niyazi, Maximilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712804/
https://www.ncbi.nlm.nih.gov/pubmed/33305269
http://dx.doi.org/10.1093/noajnl/vdaa137