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Improved risk stratification in younger IDH wild-type glioblastoma patients by combining a 4-miRNA signature with MGMT promoter methylation status
BACKGROUND: The potential benefit of risk stratification using a 4-miRNA signature in combination with MGMT promoter methylation in IDH1/2 wild-type glioblastoma patients was assessed. METHODS: Primary tumors from 102 patients with comparable treatment from the LMU Munich (n = 37), the University Ho...
Autores principales: | Unger, Kristian, Fleischmann, Daniel F, Ruf, Viktoria, Felsberg, Jörg, Piehlmaier, Daniel, Samaga, Daniel, Hess, Julia, Suresh, Marian Preetham, Mittelbronn, Michel, Lauber, Kirsten, Budach, Wilfried, Sabel, Michael, Rödel, Claus, Reifenberger, Guido, Herms, Jochen, Tonn, Jörg-Christian, Zitzelsberger, Horst, Belka, Claus, Niyazi, Maximilian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712804/ https://www.ncbi.nlm.nih.gov/pubmed/33305269 http://dx.doi.org/10.1093/noajnl/vdaa137 |
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