Infectious RNA vaccine protects mice against chikungunya virus infection

We describe a novel vaccine platform that can generate protective immunity to chikungunya virus (CHIKV) in C57BL/6J mice after a single immunization by employing an infectious RNA (iRNA), which upon introduction into a host cell launches an infectious attenuated virus. We and others have previously...

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Detalles Bibliográficos
Autores principales: Szurgot, Inga, Ljungberg, Karl, Kümmerer, Beate M., Liljeström, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712826/
https://www.ncbi.nlm.nih.gov/pubmed/33273501
http://dx.doi.org/10.1038/s41598-020-78009-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712826/
https://www.ncbi.nlm.nih.gov/pubmed/33273501
http://dx.doi.org/10.1038/s41598-020-78009-7

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