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Depletion of CD8αβ(+) T Cells in Chickens Demonstrates Their Involvement in Protective Immunity towards Marek’s Disease with Respect to Tumor Incidence and Vaccinal Protection

Marek’s disease (MD) is a lymphoproliferative disease in chickens caused by Marek’s disease virus (MDV), a highly oncogenic alphaherpesvirus. Since 1970, MD has been controlled through widespread vaccination of commercial flocks. However, repeated and unpredictable MD outbreaks continue to occur in...

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Detalles Bibliográficos
Autores principales: Umthong, Supawadee, Dunn, John R., Cheng, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712963/
https://www.ncbi.nlm.nih.gov/pubmed/32987648
http://dx.doi.org/10.3390/vaccines8040557