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Intradermal Delivery of Dendritic Cell-Targeting Chimeric mAbs Genetically Fused to Type 2 Dengue Virus Nonstructural Protein 1

Targeting dendritic cells (DCs) by means of monoclonal antibodies (mAbs) capable of binding their surface receptors (DEC205 and DCIR2) has previously been shown to enhance the immunogenicity of genetically fused antigens. This approach has been repeatedly demonstrated to enhance the induced immune r...

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Detalles Bibliográficos
Autores principales: Pereira, Lennon Ramos, Vicentin, Elaine Cristina Matos, Pereira, Sara Araujo, Maeda, Denicar Lina Nascimento Fabris, Alves, Rúbens Prince dos Santos, Andreata-Santos, Robert, de Sousa, Francielle Tramontini Gomes, Yamamoto, Marcio Massao, Castro-Amarante, Maria Fernanda, Favaro, Marianna Teixeira de Pinho, Romano, Camila Malta, Sabino, Ester Cerdeira, Boscardin, Silvia Beatriz, Ferreira, Luís Carlos de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712967/
https://www.ncbi.nlm.nih.gov/pubmed/33019498
http://dx.doi.org/10.3390/vaccines8040565