Molecular Modeling of the Shigella flexneri Serogroup 3 and 5 O-Antigens and Conformational Relationships for a Vaccine Containing Serotypes 2a and 3a

The pathogenic bacterium Shigella flexneri is a leading global cause of diarrheal disease. The O-antigen is the primary vaccine target and distinguishes the 30 serotypes reported. Except for serotype 6, all S. flexneri serotypes have a common backbone repeating unit (serotype Y), with variations in...

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Detalles Bibliográficos
Autores principales: Hlozek, Jason, Owen, Sara, Ravenscroft, Neil, Kuttel, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712985/
https://www.ncbi.nlm.nih.gov/pubmed/33147882
http://dx.doi.org/10.3390/vaccines8040643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712985/
https://www.ncbi.nlm.nih.gov/pubmed/33147882
http://dx.doi.org/10.3390/vaccines8040643

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