Enhancing the Solubility of Curcumin Using a Solid Dispersion System with Hydroxypropyl-β-Cyclodextrin Prepared by Grinding, Freeze-Drying, and Common Solvent Evaporation Methods

Cyclodextrins (CDs) and their derivatives significantly increase drug solubility by forming drug/CD complexes known as solid dispersions (SDs), which consist of an inclusion complex (IC), where the drug is entrapped within the CD cavity, and a non-IC. Here, the SDs of curcumin (CUR) and hydroxypropy...

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Detalles Bibliográficos
Autores principales: Mai, Nguyen Ngoc Sao, Nakai, Riko, Kawano, Yayoi, Hanawa, Takehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712988/
https://www.ncbi.nlm.nih.gov/pubmed/33147710
http://dx.doi.org/10.3390/pharmacy8040203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7712988/
https://www.ncbi.nlm.nih.gov/pubmed/33147710
http://dx.doi.org/10.3390/pharmacy8040203

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