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Single-cell RNA-seq reveals CD16(-) monocytes as key regulators of human monocyte transcriptional response to Toxoplasma

Monocytes are among the major myeloid cells that respond to Toxoplasma, a ubiquitous foodborne that infects ≥ 1 billion people worldwide, in human peripheral blood. As such, a molecular understanding of human monocyte-Toxoplasma interactions can expedite the development of novel human toxoplasmosis...

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Detalles Bibliográficos
Autores principales: Patir, Anirudh, Gossner, Anton, Ramachandran, Prakash, Alves, Joana, Freeman, Tom C., Henderson, Neil C., Watson, Mick, Hassan, Musa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713135/
https://www.ncbi.nlm.nih.gov/pubmed/33273621
http://dx.doi.org/10.1038/s41598-020-78250-0