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Single-cell RNA-seq reveals CD16(-) monocytes as key regulators of human monocyte transcriptional response to Toxoplasma
Monocytes are among the major myeloid cells that respond to Toxoplasma, a ubiquitous foodborne that infects ≥ 1 billion people worldwide, in human peripheral blood. As such, a molecular understanding of human monocyte-Toxoplasma interactions can expedite the development of novel human toxoplasmosis...
Autores principales: | Patir, Anirudh, Gossner, Anton, Ramachandran, Prakash, Alves, Joana, Freeman, Tom C., Henderson, Neil C., Watson, Mick, Hassan, Musa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713135/ https://www.ncbi.nlm.nih.gov/pubmed/33273621 http://dx.doi.org/10.1038/s41598-020-78250-0 |
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