Macular retinal thickness differs markedly in age-related macular degeneration driven by risk polymorphisms on chromosomes 1 and 10

The two most common genetic contributors to age-related macular degeneration (AMD), a leading cause of irreversible vision loss worldwide, are variants associated with CFH-CFHR5 on chromosome 1 (Chr1) and ARMS2/HTRA1 on chromosome 10 (Chr10). We sought to determine if risk and protective variants as...

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Detalles Bibliográficos
Autores principales: Zouache, Moussa A., Bennion, Alex, Hageman, Jill L., Pappas, Christian, Richards, Burt T., Hageman, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713215/
https://www.ncbi.nlm.nih.gov/pubmed/33273512
http://dx.doi.org/10.1038/s41598-020-78059-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713215/
https://www.ncbi.nlm.nih.gov/pubmed/33273512
http://dx.doi.org/10.1038/s41598-020-78059-x

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