Cargando…

Stability enhancement in a mAb and Fab coformulation

Multiple therapeutic proteins can be combined into a single dose for synergistic targeting to multiple sites of action. Such proteins would be mixed in dose-specific ratios to provide the correct potency for each component, and yet the formulations must also preserve their activity and keep degradat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hongyu, Dalby, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713237/
https://www.ncbi.nlm.nih.gov/pubmed/33273491
http://dx.doi.org/10.1038/s41598-020-77989-w