Stability of tuberous sclerosis complex 2 is controlled by methylation at R1457 and R1459

Mutations in genes that encode components of tuberous sclerosis complex 2 (TSC2) are associated with tuberous sclerosis complex disease. TSC2 interacts with tuberous sclerosis complex 1 to form a complex that negatively regulates cell growth and proliferation via the inactivation of mechanistic targ...

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Detalles Bibliográficos
Autores principales: Gen, Seishu, Matsumoto, Yu, Kobayashi, Ken-Ichi, Suzuki, Tsukasa, Inoue, Jun, Yamamoto, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713242/
https://www.ncbi.nlm.nih.gov/pubmed/33273660
http://dx.doi.org/10.1038/s41598-020-78274-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713242/
https://www.ncbi.nlm.nih.gov/pubmed/33273660
http://dx.doi.org/10.1038/s41598-020-78274-6

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