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Stability of tuberous sclerosis complex 2 is controlled by methylation at R1457 and R1459
Mutations in genes that encode components of tuberous sclerosis complex 2 (TSC2) are associated with tuberous sclerosis complex disease. TSC2 interacts with tuberous sclerosis complex 1 to form a complex that negatively regulates cell growth and proliferation via the inactivation of mechanistic targ...
Autores principales: | Gen, Seishu, Matsumoto, Yu, Kobayashi, Ken-Ichi, Suzuki, Tsukasa, Inoue, Jun, Yamamoto, Yuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713242/ https://www.ncbi.nlm.nih.gov/pubmed/33273660 http://dx.doi.org/10.1038/s41598-020-78274-6 |
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