TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains

The Transforming Growth Factor-β (TGFβ) signaling pathway controls transcription by regulating enhancer activity. How TGFβ-regulated enhancers are selected and what chromatin changes are associated with TGFβ-dependent enhancers regulation are still unclear. Here we report that TGFβ treatment trigger...

Descripción completa

Detalles Bibliográficos
Autores principales: Guerrero-Martínez, Jose A., Ceballos-Chávez, María, Koehler, Florian, Peiró, Sandra, Reyes, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713251/
https://www.ncbi.nlm.nih.gov/pubmed/33273453
http://dx.doi.org/10.1038/s41467-020-19877-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713251/
https://www.ncbi.nlm.nih.gov/pubmed/33273453
http://dx.doi.org/10.1038/s41467-020-19877-5

Ejemplares similares