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TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains
The Transforming Growth Factor-β (TGFβ) signaling pathway controls transcription by regulating enhancer activity. How TGFβ-regulated enhancers are selected and what chromatin changes are associated with TGFβ-dependent enhancers regulation are still unclear. Here we report that TGFβ treatment trigger...
Autores principales: | Guerrero-Martínez, Jose A., Ceballos-Chávez, María, Koehler, Florian, Peiró, Sandra, Reyes, Jose C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713251/ https://www.ncbi.nlm.nih.gov/pubmed/33273453 http://dx.doi.org/10.1038/s41467-020-19877-5 |
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