HumanaFly: high-throughput transgenesis and expression of breast cancer transcripts in Drosophila eye discovers the RPS12-Wingless signaling axis

Drosophila melanogaster has been a model for multiple human disease conditions, including cancer. Among Drosophila tissues, the eye development is particularly sensitive to perturbations of the embryonic signaling pathways, whose improper activation in humans underlies various forms of cancer. We ha...

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Detalles Bibliográficos
Autores principales: Katanaev, Vladimir L., Kryuchkov, Mikhail, Averkov, Volodymyr, Savitsky, Mikhail, Nikolaeva, Kseniya, Klimova, Nadezhda, Khaustov, Sergei, Solis, Gonzalo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713366/
https://www.ncbi.nlm.nih.gov/pubmed/33273532
http://dx.doi.org/10.1038/s41598-020-77942-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713366/
https://www.ncbi.nlm.nih.gov/pubmed/33273532
http://dx.doi.org/10.1038/s41598-020-77942-x

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