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The intracellular lipid-binding domain of human Na(+)/H(+) exchanger 1 forms a lipid-protein co-structure essential for activity
Dynamic interactions of proteins with lipid membranes are essential regulatory events in biology, but remain rudimentarily understood and particularly overlooked in membrane proteins. The ubiquitously expressed membrane protein Na(+)/H(+)-exchanger 1 (NHE1) regulates intracellular pH (pH(i)) with dy...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713384/ https://www.ncbi.nlm.nih.gov/pubmed/33273619 http://dx.doi.org/10.1038/s42003-020-01455-6 |