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Targeting REV7 effectively reverses 5-FU and oxaliplatin resistance in colorectal cancer
BACKGROUND: Despite an enormous research effort, patients diagnosed with advanced colorectal cancer (CRC) still have low prognosis after surgical resection and chemotherapy. The major obstacle for CRC treatment is chemoresistance to front line anti-cancer drugs, such as 5-fluorouracil (5-FU) and oxa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713438/ https://www.ncbi.nlm.nih.gov/pubmed/33292253 http://dx.doi.org/10.1186/s12935-020-01668-z |