Addition of L-cysteine to the N- or C-terminus of the all-D-enantiomer [(D)(KLAKLAK)(2)] increases antimicrobial activities against multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli

BACKGROUND: Antimicrobial peptides have a broad spectrum of antimicrobial activities and are attracting attention as promising next-generation antibiotics against multidrug-resistant (MDR) bacteria. The all-d-enantiomer [(D)(KLAKLAK)(2)] has been reported to have antimicrobial activity against Esche...

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Detalles Bibliográficos
Autores principales: Ohno, Maki K., Kirikae, Teruo, Yoshihara, Eisaku, Kirikae, Fumiko, Ishida, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713595/
https://www.ncbi.nlm.nih.gov/pubmed/33335804
http://dx.doi.org/10.7717/peerj.10176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713595/
https://www.ncbi.nlm.nih.gov/pubmed/33335804
http://dx.doi.org/10.7717/peerj.10176

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