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Addition of L-cysteine to the N- or C-terminus of the all-D-enantiomer [(D)(KLAKLAK)(2)] increases antimicrobial activities against multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli
BACKGROUND: Antimicrobial peptides have a broad spectrum of antimicrobial activities and are attracting attention as promising next-generation antibiotics against multidrug-resistant (MDR) bacteria. The all-d-enantiomer [(D)(KLAKLAK)(2)] has been reported to have antimicrobial activity against Esche...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713595/ https://www.ncbi.nlm.nih.gov/pubmed/33335804 http://dx.doi.org/10.7717/peerj.10176 |