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Chitinase 3–like 1 and neurofilament light chain in CSF and CNS atrophy in MS

OBJECTIVE: To investigate cross-sectional associations of CSF levels of neurofilament light chain (NfL) and of the newly emerging marker chitinase 3–like protein 1 (CHI3L1) with brain and spinal cord atrophy, which are established MRI markers of disease activity in MS, to study CHI3L1 and NfL in rel...

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Detalles Bibliográficos
Autores principales: Schneider, Ruth, Bellenberg, Barbara, Gisevius, Barbara, Hirschberg, Sarah, Sankowski, Roman, Prinz, Marco, Gold, Ralf, Lukas, Carsten, Haghikia, Aiden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713721/
https://www.ncbi.nlm.nih.gov/pubmed/33172960
http://dx.doi.org/10.1212/NXI.0000000000000906