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Longitudinal expression changes are weak correlates of disease progression in Huntington’s disease

Huntington’s disease is a severe but slowly progressive hereditary illness for which only symptomatic treatments are presently available. Clinical measures of disease progression are somewhat subjective and may require years to detect significant change. There is a clear need to identify more sensit...

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Detalles Bibliográficos
Autores principales: Mitchell, Christopher T, Krier, Irina, Arjomand, Jamshid, Borowsky, Beth, Tabrizi, Sarah J, Leavitt, Blair R, Luthi-Carter, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713990/
https://www.ncbi.nlm.nih.gov/pubmed/33305259
http://dx.doi.org/10.1093/braincomms/fcaa172