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Role of glucosamine in development of diabetic neuropathy independent of the aldose reductase pathway

Long-term metabolic aberrations contribute to the development of diabetic neuropathy but the precise mechanism or mechanisms remains elusive. We have previously shown that aldose reductase-deficient mice exhibit delayed onset and progression of neuropathy following induction of diabetes, suggesting...

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Detalles Bibliográficos
Autores principales: Mizukami, Hiroki, Osonoi, Sho, Takaku, Shizuka, Yamagishi, Shin-Ichiro, Ogasawara, Saori, Sango, Kazunori, Chung, Sookja, Yagihashi, Soroku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713992/
https://www.ncbi.nlm.nih.gov/pubmed/33305258
http://dx.doi.org/10.1093/braincomms/fcaa168