LC-MS based stability-indicating method for studying the degradation of lonidamine under physical and chemical stress conditions

BACKGROUND AND PURPOSE: Lonidamine is a hexokinase II inhibitor, works as an anticancer molecule, and is extensively explored in clinical trials. Limited information prevails about the stability-indicating methods which could determine the forced degradation of lonidamine under stressed conditions....

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Detalles Bibliográficos
Autores principales: Rochani, Ankit Kanaiyalal, Wheatley, Margaret, Oeffinger, Brian Edward, Eisenbrey, John Robert, Kaushal, Gagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714013/
https://www.ncbi.nlm.nih.gov/pubmed/33312209
http://dx.doi.org/10.4103/1735-5362.293509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714013/
https://www.ncbi.nlm.nih.gov/pubmed/33312209
http://dx.doi.org/10.4103/1735-5362.293509

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