A Two-Step Process of Effector Programming Governs CD4(+) T Cell Fate Determination Induced by Antigenic Activation in the Steady State

Various processes induce and maintain immune tolerance, but effector T cells still arise under minimal perturbations of homeostasis through unclear mechanisms. We report that, contrary to the model postulating primarily tolerogenic mechanisms initiated under homeostatic conditions, effector programm...

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Detalles Bibliográficos
Autores principales: Opejin, Adeleye, Surnov, Alexey, Misulovin, Ziva, Pherson, Michelle, Gross, Cindy, Iberg, Courtney A., Fallahee, Ian, Bourque, Jessica, Dorsett, Dale, Hawiger, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714042/
https://www.ncbi.nlm.nih.gov/pubmed/33238127
http://dx.doi.org/10.1016/j.celrep.2020.108424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714042/
https://www.ncbi.nlm.nih.gov/pubmed/33238127
http://dx.doi.org/10.1016/j.celrep.2020.108424

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