Interaction of amyloid beta with humanin and acetylcholinesterase is modulated by ATP

Humanin (HN) is known to bind amyloid beta (Aβ)‐inducing cytoprotective effects, while binding of acetylcholinesterase (AChE) to Aβ increases its aggregation and cytotoxicity. Previously, we showed that binding of HN to Aβ blocks aggregation induced by AChE and that HN decreases but does not abolish...

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Detalles Bibliográficos
Autores principales: Atali, Sarah, Dorandish, Sadaf, Devos, Jonathan, Williams, Asana, Price, Deanna, Taylor, Jaylen, Guthrie, Jeffrey, Heyl, Deborah, Evans, Hedeel Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714071/
https://www.ncbi.nlm.nih.gov/pubmed/33145964
http://dx.doi.org/10.1002/2211-5463.13023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714071/
https://www.ncbi.nlm.nih.gov/pubmed/33145964
http://dx.doi.org/10.1002/2211-5463.13023

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