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Inhibition properties of free and conjugated leupeptin analogues

Leupeptin is a naturally occurring inhibitor of various proteases, in particular serine proteases. Following its discovery, the inhibitory properties of several other peptidyl argininals have been studied. The specificity of leupeptin is most likely due to the Leu–Leu–Argininal sequence, and its C‐t...

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Detalles Bibliográficos
Autores principales: Billinger, Erika, Viljanen, Johan, Lind, Sara Bergström, Johansson, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714073/
https://www.ncbi.nlm.nih.gov/pubmed/33016476
http://dx.doi.org/10.1002/2211-5463.12994