SHP2 knockdown ameliorates liver insulin resistance by activating IRS‐2 phosphorylation through the AKT and ERK1/2 signaling pathways

Diabetes is a chronic metabolic disease characterized by insulin resistance (IR). SHP2 has previously been identified as a potential target to reduce IR in diabetes. Here, we examined the effects of SHP2 on glucose consumption (GC), IR level and the expression of insulin receptor substrate (IRS), AK...

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Detalles Bibliográficos
Autores principales: Yue, Xinxin, Han, Tao, Hao, Wei, Wang, Min, Fu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714075/
https://www.ncbi.nlm.nih.gov/pubmed/33012117
http://dx.doi.org/10.1002/2211-5463.12992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714075/
https://www.ncbi.nlm.nih.gov/pubmed/33012117
http://dx.doi.org/10.1002/2211-5463.12992

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