Analysis of the effects of a tricyclic antidepressant on secondary sleep disturbance induced by chronic pain in a preclinical model

Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously. In our previous study, we suggested that hyperactivation of ascending serotonergic neurons could cause seco...

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Detalles Bibliográficos
Autores principales: Ito, Hisakatsu, Takemura, Yoshinori, Aoki, Yuta, Hattori, Mizuki, Horikawa, Hideyo, Yamazaki, Mitsuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714178/
https://www.ncbi.nlm.nih.gov/pubmed/33270791
http://dx.doi.org/10.1371/journal.pone.0243325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714178/
https://www.ncbi.nlm.nih.gov/pubmed/33270791
http://dx.doi.org/10.1371/journal.pone.0243325

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