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Analysis of the effects of a tricyclic antidepressant on secondary sleep disturbance induced by chronic pain in a preclinical model
Chronic pain and sleep have a bidirectional relationship that promotes a vicious circle making chronic pain more difficult to treat. Therefore, pain and sleep should be treated simultaneously. In our previous study, we suggested that hyperactivation of ascending serotonergic neurons could cause seco...
Autores principales: | Ito, Hisakatsu, Takemura, Yoshinori, Aoki, Yuta, Hattori, Mizuki, Horikawa, Hideyo, Yamazaki, Mitsuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714178/ https://www.ncbi.nlm.nih.gov/pubmed/33270791 http://dx.doi.org/10.1371/journal.pone.0243325 |
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