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Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension

The pathophysiological mechanisms underlying chronic thromboembolic pulmonary hypertension (CTEPH) are still unclear. Endothelial cell (EC) remodeling is believed to contribute to this pulmonary disease triggered by thrombus and hemodynamic forces disbalance. Recently, we showed that HSP70 levels de...

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Detalles Bibliográficos
Autores principales: Salibe-Filho, William, Araujo, Thaís L. S., G. Melo, Everton, B. C. T. Coimbra, Luiza, Lapa, Monica S., Acencio, Milena M. P., Freitas-Filho, Orival, Capelozzi, Vera Luiza, Teixeira, Lisete Ribeiro, Fernandes, Caio J. C. S., Jatene, Fabio Biscegli, Laurindo, Francisco R. M., Terra-Filho, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714249/
https://www.ncbi.nlm.nih.gov/pubmed/33270690
http://dx.doi.org/10.1371/journal.pone.0242960