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Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension
The pathophysiological mechanisms underlying chronic thromboembolic pulmonary hypertension (CTEPH) are still unclear. Endothelial cell (EC) remodeling is believed to contribute to this pulmonary disease triggered by thrombus and hemodynamic forces disbalance. Recently, we showed that HSP70 levels de...
Autores principales: | Salibe-Filho, William, Araujo, Thaís L. S., G. Melo, Everton, B. C. T. Coimbra, Luiza, Lapa, Monica S., Acencio, Milena M. P., Freitas-Filho, Orival, Capelozzi, Vera Luiza, Teixeira, Lisete Ribeiro, Fernandes, Caio J. C. S., Jatene, Fabio Biscegli, Laurindo, Francisco R. M., Terra-Filho, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714249/ https://www.ncbi.nlm.nih.gov/pubmed/33270690 http://dx.doi.org/10.1371/journal.pone.0242960 |
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