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Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival

Liver kinase B1 (LKB1), also known as serine/threonine kinase 11 (STK11) is the major energy sensor for cells to respond to metabolic stress. Autophagy degrades and recycles proteins, macromolecules, and organelles for cells to survive starvation. To assess the role and cross-talk between autophagy...

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Detalles Bibliográficos
Autores principales: Khayati, Khoosheh, Bhatt, Vrushank, Hu, Zhixian Sherrie, Fahumy, Sajid, Luo, Xuefei, Guo, Jessie Yanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714393/
https://www.ncbi.nlm.nih.gov/pubmed/33236987
http://dx.doi.org/10.7554/eLife.62377