Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis

Resident vascular adventitial SCA1(+) progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior in homeostasis and injury responses. Using smoot...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Sizhao, Jolly, Austin J., Strand, Keith A., Dubner, Allison M., Mutryn, Marie F., Moulton, Karen S., Nemenoff, Raphael A., Majesky, Mark W., Weiser-Evans, Mary C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714399/
https://www.ncbi.nlm.nih.gov/pubmed/33119549
http://dx.doi.org/10.1172/jci.insight.139445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714399/
https://www.ncbi.nlm.nih.gov/pubmed/33119549
http://dx.doi.org/10.1172/jci.insight.139445

Ejemplares similares