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Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis

Resident vascular adventitial SCA1(+) progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior in homeostasis and injury responses. Using smoot...

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Detalles Bibliográficos
Autores principales:	Lu, Sizhao, Jolly, Austin J., Strand, Keith A., Dubner, Allison M., Mutryn, Marie F., Moulton, Karen S., Nemenoff, Raphael A., Majesky, Mark W., Weiser-Evans, Mary C.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714399/ https://www.ncbi.nlm.nih.gov/pubmed/33119549 http://dx.doi.org/10.1172/jci.insight.139445

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