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Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction

Understanding the distinct pathogenic mechanisms that culminate in allograft fibrosis and chronic graft failure is key in improving outcomes after solid organ transplantation. Here, we describe an F1 → parent orthotopic lung transplant model of restrictive allograft syndrome (RAS), a particularly fu...

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Detalles Bibliográficos
Autores principales: Misumi, Keizo, Wheeler, David S., Aoki, Yoshiro, Combs, Michael P., Braeuer, Russell R., Higashikubo, Ryuji, Li, Wenjun, Kreisel, Daniel, Vittal, Ragini, Myers, Jeffrey, Lagstein, Amir, Walker, Natalie M., Farver, Carol F., Lama, Vibha N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714414/
https://www.ncbi.nlm.nih.gov/pubmed/33268593
http://dx.doi.org/10.1172/jci.insight.136533