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Phlorizin ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity

Phlorizin (PHZ) is one of phytonutrients in apples that contributes to the health-promoting effect implicated by the saying, ‘an apple a day keeps the doctor away’. PHZ was firstly identified as a competitive inhibitor of sodium-glucose co-transporters-2 (SGLT2); however, its low bioavailability mak...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Yu, Chen, Jiang, Yi, Kang, Peng, Ling, Xie, Jie, Gou, Xun, Peng, Tong, Tang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714487/
https://www.ncbi.nlm.nih.gov/pubmed/33222603
http://dx.doi.org/10.1080/19490976.2020.1842990