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Phlorizin ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity
Phlorizin (PHZ) is one of phytonutrients in apples that contributes to the health-promoting effect implicated by the saying, ‘an apple a day keeps the doctor away’. PHZ was firstly identified as a competitive inhibitor of sodium-glucose co-transporters-2 (SGLT2); however, its low bioavailability mak...
Autores principales: | Zhang, Xiao-Yu, Chen, Jiang, Yi, Kang, Peng, Ling, Xie, Jie, Gou, Xun, Peng, Tong, Tang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714487/ https://www.ncbi.nlm.nih.gov/pubmed/33222603 http://dx.doi.org/10.1080/19490976.2020.1842990 |
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