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Is the survival of patients treated with ipilimumab affected by antibiotics? An analysis of 1585 patients from the French National hospital discharge summary database (PMSI)

Background: The gut microbiota has a key role in the regulation of the immune system. Disruption of the gut microbiota’s composition by antibiotics might significantly affect the efficacy of immune checkpoint inhibitors. In a study of patients treated with ipilimumab, we sought to assess the relatio...

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Detalles Bibliográficos
Autores principales: Cren, Pierre-Yves, Bertrand, Nicolas, Le Deley, Marie-Cécile, Génin, Michaël, Mortier, Laurent, Odou, Pascal, Penel, Nicolas, Chazard, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714497/
https://www.ncbi.nlm.nih.gov/pubmed/33299658
http://dx.doi.org/10.1080/2162402X.2020.1846914