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Cyclin D3 Governs Clonal Expansion of Dark Zone Germinal Center B Cells
Germinal center (GC) B cells surge in their proliferative capacity, which poses a direct risk for B cell malignancies. G1- to S-phase transition is dependent on the expression and stability of D-type cyclins. We show that cyclin D3 expression specifically regulates dark zone (DZ) GC B cell prolifera...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714654/ https://www.ncbi.nlm.nih.gov/pubmed/33207194 http://dx.doi.org/10.1016/j.celrep.2020.108403 |