Cargando…

Cyclin D3 Governs Clonal Expansion of Dark Zone Germinal Center B Cells

Germinal center (GC) B cells surge in their proliferative capacity, which poses a direct risk for B cell malignancies. G1- to S-phase transition is dependent on the expression and stability of D-type cyclins. We show that cyclin D3 expression specifically regulates dark zone (DZ) GC B cell prolifera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramezani-Rad, Parham, Chen, Cindi, Zhu, Zilu, Rickert, Robert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714654/ https://www.ncbi.nlm.nih.gov/pubmed/33207194 http://dx.doi.org/10.1016/j.celrep.2020.108403

Ejemplares similares

The AKT isoforms 1 and 2 drive B cell fate decisions during the germinal center response
por: Zhu, Zilu, et al.
Publicado: (2019)

Quick and easy purification of murine untouched naive B cells or germinal center B cells by MACS
por: Ramezani-Rad, Parham, et al.
Publicado: (2021)

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells
por: Pae, Juhee, et al.
Publicado: (2020)

Remodeling of light and dark zone follicular dendritic cells governs germinal center responses
por: Pikor, Natalia B, et al.
Publicado: (2020)

TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone
por: Albright, Anne R., et al.
Publicado: (2019)

IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation
por: Petersone, Lina, et al.
Publicado: (2023)

Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging
por: Stewart, Isabelle, et al.
Publicado: (2018)

TLR4 signaling augments B lymphocyte migration and overcomes the restriction that limits access to germinal center dark zones
por: Hwang, Il-Young, et al.
Publicado: (2009)

Expression of the Plasma Cell Transcriptional Regulator Blimp-1 by Dark Zone Germinal Center B Cells During Periods of Proliferation
por: Radtke, Daniel, et al.
Publicado: (2019)

Positive Selection in the Light Zone of Germinal Centers
por: Nakagawa, Rinako, et al.
Publicado: (2021)

Clonal germinal center B cells function as a niche for T-cell lymphoma
por: Fujisawa, Manabu, et al.
Publicado: (2022)

A Spatially Resolved Dark- versus Light-Zone Microenvironment Signature Subdivides Germinal Center-Related Aggressive B Cell Lymphomas
por: Tripodo, Claudio, et al.
Publicado: (2020)

Complexes of D-type cyclins with CDKs during maize germination
por: Godínez-Palma, Silvia K., et al.
Publicado: (2013)

Role of E-cadherin and cyclin D1 as predictive markers of aggression and clonal expansion in head and neck squamous cell carcinoma
por: Shergill, Khushdeep, et al.
Publicado: (2018)

GSK3 is a metabolic checkpoint regulator in B cells
por: Jellusova, Julia, et al.
Publicado: (2017)

Regnase-1 is essential for B cell homeostasis to prevent immunopathology
por: Bhat, Numana, et al.
Publicado: (2021)

Capturing change in clonal composition amongst single mouse germinal centers
por: Firl, Daniel J, et al.
Publicado: (2018)

A Population Dynamics Model for Clonal Diversity in a Germinal Center
por: Amitai, Assaf, et al.
Publicado: (2017)

Vaccination establishes clonal relatives of germinal center T cells in the blood of humans
por: Heit, Antje, et al.
Publicado: (2017)

Germinal Center Centroblasts Transition to a Centrocyte Phenotype According to a Timed Program and Depend on the Dark Zone for Effective Selection
por: Bannard, Oliver, et al.
Publicado: (2013)

Germinal Center Centroblasts Transition to a Centrocyte Phenotype According to a Timed Program and Depend on the Dark Zone for Effective Selection
por: Bannard, Oliver, et al.
Publicado: (2013)

Augmented Expression of a Human Gene for 8-oxoguanine DNA Glycosylase (MutM) in B Lymphocytes of the Dark Zone in Lymph Node Germinal Centers
por: Kuo, Frank C., et al.
Publicado: (1997)

Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers
por: Meyer-Hermann, Michael, et al.
Publicado: (2018)

Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting
por: Mesin, Luka, et al.
Publicado: (2020)

Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers
por: Castrillon, Carlos, et al.
Publicado: (2023)

Germinal center B cells govern their own fate via antibody feedback
por: Zhang, Yang, et al.
Publicado: (2013)

In Vivo Clonal Analysis Reveals Development Heterogeneity of Oligodendrocyte Precursor Cells Derived from Distinct Germinal Zones
por: Liu, Rui, et al.
Publicado: (2021)

Computational Model Reveals a Stochastic Mechanism behind Germinal Center Clonal Bursts
por: Pélissier, Aurélien, et al.
Publicado: (2020)

Role of affinity in plasma cell development in the germinal center light zone
por: ElTanbouly, Mohamed A., et al.
Publicado: (2023)

Antiviral Protection and Germinal Center Formation, But Impaired B Cell Memory in the Absence of CD19
por: Fehr, Thomas, et al.
Publicado: (1998)

How oligoclonal are germinal centers? A new method for estimating clonal diversity from immunohistological sections
por: Faro, Jose, et al.
Publicado: (2013)

Marginal zone SIGN-R1(+) macrophages are essential for the maturation of germinal center B cells in the spleen
por: Pirgova, Gabriela, et al.
Publicado: (2020)

Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection
por: Chen, Chao, et al.
Publicado: (2018)

A cyclin D1-positive diffuse large B-cell lymphoma of germinal center B-cell-like subtype in the right tonsil: A rare case report
por: Jiang, Changrui, et al.
Publicado: (2017)

Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice
por: Kil, Laurens P., et al.
Publicado: (2019)

Gradient expansion(s) and dark energy
por: Giovannini, Massimo
Publicado: (2005)

Germinal Center Cells Turning to the Dark Side: Neoplasms of B Cells, Follicular Helper T Cells, and Follicular Dendritic Cells
por: Munguía-Fuentes, Rosario, et al.
Publicado: (2021)

Clonal expansion of abnormal B cells in old NZB mice
Publicado: (1987)

Clonal expansion in B-CLL: Fungal drivers or self-service?
por: Greaves, Mel
Publicado: (2013)

The analysis of clonal expansions in normal and autoimmune B cell repertoires
por: Hershberg, Uri, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hueepqrsku1gdchqlu24c91q3f