SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer

Metastatic breast cancer (MBC) is an extremely recalcitrant disease capable of bypassing current targeted therapies via engagement of several growth promoting pathways. SH2 containing protein tyrosine phosphatase-2 (SHP2) is an oncogenic phosphatase known to facilitate growth and survival signaling...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Libring, Sarah, Ruddraraju, Kasi Viswanatharaju, Miao, Jinmin, Solorio, Luis, Zhang, Zhong-Yin, Wendt, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714690/
https://www.ncbi.nlm.nih.gov/pubmed/33033382
http://dx.doi.org/10.1038/s41388-020-01488-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714690/
https://www.ncbi.nlm.nih.gov/pubmed/33033382
http://dx.doi.org/10.1038/s41388-020-01488-5

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